科学研究情况简介 |
【近5年来主要研究课题】 多功能改性高分子材料的生物医用研究 可持续释放抗癌药的呼吸外科胶粘剂的研发 高效医用组织密封胶的产业转化项目 【近5年来项目】 国家自然科学基金青年基金(2023-2025年),主持 中央高校自主科研计划青年基金(2022-2023年),主持 企业博后及企业横向科研多项(2021-至今),主持 【近5年来代表性论文第一作者】 1) Deyan Du#, Xi Chen#, Chang Shi, Zhuying Zhang, Dongjian Shi*, Daisaku Kaneko, Tatsuo Kaneko, Zhen Hua. Mussel-inspired epoxy bioadhesive with enhanced interfacial interactions for wound repair. Acta Biomaterialia 2021, 136: 223-232. (JCR 1区, IF: 10.6) 2) Xi Chen, Tetsushi Taguchi*. Enhanced skin adhesive property of α-cyclodextrin/nonanyl group-modified poly(vinyl alcohol) inclusion complex film. Carbohydrate Polymers 2021, 263: 117993. (JCR 1区, IF: 10.7) 3) Xi Chen, Tetsushi Taguchi*. Bonding a titanium plate and soft tissue interface by using an adhesive bone paste composed of α-tricalcium phosphate and α-cyclodextrin/nonanyl group-modified poly(vinyl alcohol) inclusion complex. Colloids and Surfaces B: Biointerfaces 2021, 203: 111757. (JCR 1区, IF: 6.0, 论文被选为杂志封面) 4) Xi Chen, Wendi Yang, Jingjing Zhang, Li Zhang, Heyun Shen, Dongjian Shi*. Alkalinity triggered the degradation of polydopamine nanoparticles. Polymer Bulletin 2021, 78(8): 4439-4452. 5) Xi Chen, Tetsushi Taguchi*. Enhanced skin adhesive property of electrospun α-cyclodextrin/nonanyl group-modified poly(vinyl alcohol) inclusion complex fiber sheet. RSC Advances 2021, 11(15): 8759-8766. 6) Xi Chen, Akihiro Nishiguchi, Tetsushi Taguchi*. Adhesive submucosal injection material based on the nonanal group-modified poly(vinyl alcohol)/α-cyclodextrin inclusion complex for endoscopic submucosal dissection. ACS Applied Bio Materials 2020, 3(7): 4370-4379. 7) Xi Chen, Tetsushi Taguchi*. Enhanced skin adhesive property of hydrophobically modified poly(vinyl alcohol) films. ACS OMEGA 2020, 5(3): 1519-1527. (论文被选为 ACS Weekly Press 的新闻稿主题) 8) Xi Chen, Tetsushi Taguchi*. Injectable inclusion complex composed of α-cyclodextrin and hydrophobically modified poly(vinyl alcohol) as a cerebral aneurysm embolization material. Polymer Journal 2020, 52(7): 793–802. 9) Chang Shi#, Xi Chen#, Zhuying Zhang, Qihao Chen, Dongjian Shi*, Daisaku Kaneko. Mussel inspired bio-adhesive with multi-interactions for tissue repair. Journal of Biomaterials Science, Polymer Edition 2020, 31(4): 491-503. 10) Xi Chen, Tetsushi Taguchi*. Injectable, non-diffusible and pre-filled bone paste composed of α-tricalcium phosphate and hydrophobically modified poly(vinyl alcohol). Advanced Engineering Materials 2019, 21(11): 1900660. 11) Xi Chen, Ryo Mizuta, Naoki Fukata, Tetsushi Taguchi*. Design of bio-inspired adhesive surface composed of hexanoyl group-modified gelatin and silicon nanowire. Colloids and Surfaces B: Biointerfaces 2019, 178: 111-119. (JCR 1区, IF: 6.0) 12) Xi Chen, Tetsushi Taguchi*. Hydrophobically modified poly(vinyl alcohol)s as antithrombogenic coating materials. Materials Science and Engineering: C 2019, 102: 289-298. (JCR 1区, IF: 7.3) 【近5年内发表的其他论著】 13) Hiroaki Ichimaru, Yosuke Mizuno, Xi Chen, Akihiro Nishiguchi, Tetsushi Taguchi*. Prevention of pulmonary air leaks using a biodegradable tissue-adhesive fiber sheet based on Alaska pollock gelatin modified with decanyl groups. Biomaterials Science 2021, 9(3): 861-873. (JCR 1区, IF: 7.6) 14) Ryo Mizuta, Yosuke Mizuno, Xi Chen, Yukari Kurihara, Tetsushi Taguchi*. Evaluation of an octyl group-modified Alaska pollock gelatin-based surgical sealant for prevention of postoperative adhesion. Acta Biomaterialia 2021, 121: 328-338. (JCR 1区, IF: 10.6) 15) Shusuke Masuda, Taku Suzuki*, Shinsuke Shibata, Nobuko Moritoki, Yoshifumi Abe, Xi Chen, Yosuke Mizuno, Akihiro Nishiguchi, Hiroo Kimura, Noboru Matsumura, Takuji Iwamoto, Tetsushi Taguchi*, Morio Matsumoto, Masaya Nakamura. A novel Alaska pollock gelatin sealant shows higher bonding strength and nerve regeneration comparable to that of fibrin sealant in a cadaveric model and a rat model. Plastic and Reconstructive Surgery 2021, 148(5): 742e-752e. (JCR 1区, IF: 5.1) 【主要学术及转化奖励】 1. 无锡市新吴区 “飞凤人才” 培育类项目(1/4) 2. TGSW-IWP, “Best Presentation Award” 获奖排序(1/4) 3. 日本生物材料学会第41届年会, “优秀研究海报奖” 获奖排序(1/2) 4. 日本筑波生物医学工程合作论坛2020, “研究奖励奖” 获奖排序(1/3) |